Which patient group (or groups) should avoid using NSAIDs

a)     Kidney disease
b)    Myocardial infarction
c)     Irritable bowel syndrome
d)    All of the above

Answer:

All of the above

NSAIDs:

NSAIDs should be avoided in the following group of patients: Those with renal disease and those who have an increased risk of gastrointestinal bleeding.

NSAIDs – with the exception of aspirin – increase the risk of heart attack and bleeding in patients with pre-existing conditions. This group of medications should be avoided in those who have a history of kidney disease because they increase the likelihood of renal failure. They are also contraindicated in patients with a history of peptic ulcer disease, coagulation abnormalities, or potential cardiovascular problems.

Risk Factors of NSAIDs

Risk factors for NSAID use include:

Ø Existing heart disease, including angina and a recent heart attack

Ø Cardiovascular disease risk factors, such as high blood pressure or diabetes

Ø Kidney problems, such as kidney failure or failure to pass urine

Ø Liver disease, including hepatitis and cirrhosis of the liver

Ø Stomach ulcers or other reasons to avoid aspirin

Ø History of bleeding problems

Uses of NSAIDs

NSAIDs are used in many ways:

To reduce pain and inflammation caused by arthritis, injury, or other musculoskeletal problems. Because NSAIDs can cause bleeding problems, they're usually reserved for short-term use.